Study
HBOT Reduces Vascular Dysfunction and Amyloid Burden (Alzheimer’s Mouse Model)
HBOT: CBF↑, hypoxia↓; in AD mice, amyloid↓. In elderly patients (n=6), CBF and cognitive scores improved after 60 sessions (2 ATA, 90 min).
Lesezeit:
1
min.
Can Hyperbaric Oxygen Therapy (HBOT) Protect Brain Function as We Age and Even Slow the Progression of Alzheimer’s?
A recent scientific study provides striking evidence of the positive effects of HBOT in age-related cognitive decline and Alzheimer’s disease.
What is Hyperbaric Oxygen Therapy?
In HBOT, patients breathe pure oxygen in a pressurized chamber. This allows much more oxygen to be absorbed into the blood than under normal conditions—a process that supports healing and cellular health.
Study Shows: HBOT Benefits the Brain
In a groundbreaking study, researchers examined both an Alzheimer’s disease mouse model and elderly individuals with memory problems. They investigated how HBOT affects cerebral blood flow, oxygen supply, and amyloid plaques—the protein deposits that are characteristic of Alzheimer’s.
Key Findings
Improved cerebral blood flow:
After HBOT, significant blood vessel dilation and a marked increase in brain blood flow were observed. This improves oxygen delivery and reduces chronic hypoxia, which is particularly harmful in Alzheimer’s disease.
Reduction of amyloid plaques:
In mice, treatment not only reduced existing deposits but also slowed the formation of new plaques. These changes were associated with improved cognitive performance.
Positive effects in elderly patients:
Older individuals with existing memory impairments also benefited: after HBOT, they showed better cerebral blood flow and improved cognitive test results.
What Do These Results Mean?
The findings suggest that HBOT could become a promising adjunct in the prevention or treatment of age-related memory decline and Alzheimer’s disease. By enhancing oxygen delivery, HBOT may help sustain brain function as we age.
Original Study on PubMed
For detailed scientific insights, see the official PubMed entry:
Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients (PubMed ID: 34499614)
Conclusion
HBOT may represent a new avenue of hope for age-related dementia and Alzheimer’s disease. Early clinical studies show improvements in brain perfusion, reduction of harmful deposits, and enhanced cognitive performance.
⚠️ Important: Always consult your physician before considering new therapeutic approaches, as individual responses may vary.
Autoren
Ronit Shapira; Amos Gdalyahu; Irit Gottfried; Efrat Sasson; Amir Hadanny; Shai Efrati; Pablo Blinder; Uri Ashery.
Publikations Details
Studientyp:
Präklinisch (5XFAD-Maus) + prospektive, einarmige Human-Pilotstudie (prä-post).
Publikation:
Aging (Albany NY) 2021; 13(17); Epub 09.09.2021.
Teilnehmer:
(Human): n=6, Ø 70 J., Gedächtnis-Score < 100.
Ort:
Tel Aviv University & Sagol Center for Hyperbaric Medicine, Israel.
Seiten:
DOI:
PubMed ID:
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